Big Bang Theory Quote
Sheldon: He's holding the phone to his left ear. Ears do not cross hemispheres, so he's using the analytical rather than the emotional side of the brain, suggesting that he has no personal relationship with the caller.
Leonard: No, I didn't realize it had been so long... Sure, I guess there's no other choice but just to go ahead and do it.
Sheldon: He's referrng to an activity he has done before. It's unpleasant and needs to be repeated. This suggests some sort of invasive medical test like perhaps a colonoscopy.
Leonard: Aren't there any other options? There's not a lot of room. It's going to be uncomfortable.
Sheldon: Yes, yes, I'm definitely going with colonoscopy.
Leonard: Okay, bye.
(Leonard looks up to see everyone looking at him)
Leonard: My mother's coming to visit.
Howard: (to Sheldon) How about that, you were right.
Quote from S02E15 - The Maternal Capacitance